Use of deep learning to detect personalized spatial-frequency abnormalities in EEGs of children with ADHD
Objective . Attention-deficit/hyperactivity disorder (ADHD) is one of the most prevalent
neurobehavioral disorders. Studies have tried to find the neural correlations of ADHD with
electroencephalography (EEG). Due to the heterogeneity in the ADHD population, a multivariate EEG
profile is useful, and the detection of a personalized abnormality in EEG is urgently needed. Deep
learning algorithms, especially convolutional neural network (CNN), have made tremendous progress
recently, and are expected to solve the problem. Approach . We adopted CNN techniques and a
visualization technique named gradient-weighted class activation mapping (Grad-CAM) for detecting a
personalized spatial-frequency abnormality in EEGs of ADHD children. A total of 50 children with
ADHD (nine girls, mean age: 10.44 ± 0.75) and 57 controls who were matched for age and handedness
were recruited. The power spectrum density of EEGs was used as input. We presented an intuitive form
of representing...